{"id":1451,"date":"2025-01-07T13:14:43","date_gmt":"2025-01-07T12:14:43","guid":{"rendered":"https:\/\/ptb-rug.com\/?page_id=1451"},"modified":"2026-03-03T12:25:19","modified_gmt":"2026-03-03T11:25:19","slug":"publications","status":"publish","type":"page","link":"https:\/\/ptb-rug.com\/?page_id=1451","title":{"rendered":"Publications"},"content":{"rendered":"\t\t
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See Past Publications \u2013 Department of Pharmaceutical Technology and Biopharmacy<\/h3>\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t
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2026<\/h3>
Clinical utility of blood-based biomarkers in pregnant women with inflammatory bowel disease.<\/div>
Holstein HJ, Bouwknegt DG, Gordijn SJ, Dijkstra G, Cantineau AEP, Mian P, van Goor H, Visschedijk MC, Bourgonje AR<\/span> \u2014 DOI: 10.1080\/14737159.2026.2661745<\/a><\/div><\/div>
Simulation of Imatinib Pharmacokinetics in pregnant women with chronic myeloid leukemia in the third trimester.<\/div>
Mian P, Lok CAR, Dontje AEWK, Prins JR, Oude Munnink TH, Nieuwenhuizen L, Gordijn SJ, Touw DJ, Malik P<\/span> \u2014 DOI: 10.1007\/s00228-026-04049-z<\/a><\/div><\/div>
Cryomilling of freeze dried low-Tg sugar glasses: A versatile method to prepare inhalable dry powder formulations.<\/div>
Jansen EM, Posthumus SAE, Chan MKT, Beertema M, Mulia KF, Frijlink HW, Hinrichs WLJ<\/span> \u2014 DOI: 10.1016\/j.ejpb.2026.115065<\/a><\/div><\/div>
Generation and viability evaluation of human precision-cut placental slices for ex vivo studies.<\/div>
Wang H, Pierik E, Schoots M, Wijmans C, Hammond J, Elzinga F, Vos M, Gordijn S, Touw D, Prins JR, Olinga P, Mian P<\/span> \u2014 DOI: 10.1016\/j.placenta.2026.03.008<\/a><\/div><\/div>
Regenerative therapeutics for chronic obstructive pulmonary disease.<\/div>
van der Koog L, Showell HRD, Nugraha DF, Lehmann M, Conlon TM, Yildirim A\u00d6, Fuentes-Mateos R, Baarsma H, Ng-Blichfeldt JP, Melgert BN, Dost AFM, Burgess JK, Yam SLS, Heijink IH, Ahmed S, Paschini M, Jansen EM, Hinrichs WLJ, Johnson JR, Wu X, Nagelkerke A, Frijlink HW, Kim CF, Gosens R<\/span> \u2014 DOI: 10.1016\/j.pharmr.2026.100124<\/a><\/div><\/div>
Receptor agonist of NF\u03baB signaling ligand directs lung epithelial cell expansion through RANK signaling.<\/div>
Habibie H, Vlasma JR, Putri KSS, Song S, de Jager MH, Petersen A, Boorsma CE, Cool RH, Quax W, Nawijn MC, Timens W, Burgess JK, Brandsma CA, Melgert BN<\/span> \u2014 DOI: 10.1152\/ajplung.00176.2025<\/a><\/div><\/div>
Freeze-Drying in Sucrose Followed by Cryomilling Enables the Formulation of sa-mRNA-LNP Powders for Inhalation.<\/div>
Jansen EM, Ruigrok MJR, Suh MS, Ruppel PM, Cui X, Opsomer L, Sanders NN, Frijlink HW, Hinrichs WLJ<\/span> \u2014 DOI: 10.3390\/pharmaceutics18010121<\/a><\/div><\/div>
Inter-species variability in 4,4'-methylenedianiline metabolism: insights from human and rat precision-cut liverslices.<\/div>
Hof MAJ, Sewdihal J, Stepanovic S, Hermans JH, Horvatovich P, Olinga P, Klont F<\/span> \u2014 DOI: 10.1016\/j.yrtph.2026.106034<\/a><\/div><\/div>
Gradient in Motion: Mechanical Stimulation Of Cells Cultured on Melt Electrowritten Scaffolds.<\/div>
Zieli\u0144ski PS, Gudeti PKR, Koch M, Olinga P, Kamperman M, W\u0142odarczyk-Biegun MK<\/span> \u2014 DOI: 10.1016\/j.actbio.2025.12.053<\/a><\/div><\/div>
Identification of Subtype-Specific Vulnerabilities in Resistant Glioblastoma: A Computational Pipeline for Biomarkers and Drug Discovery.<\/div>
Lopez-Parra JS, Hameedat F, Sousa SF, Walenkamp AME, Sousa F, A Santos H<\/span> \u2014 DOI: 10.1021\/acs.molpharmaceut.5c01538<\/a><\/div><\/div>
Osteoprotegerin Is Elevated in Pulmonary Fibrosis and Associates with Idiopathic Pulmonary Fibrosis Progression: A Pilot Study.<\/div>
Habibie H, Putri KSS, Boorsma CE, Brass DM, Heukels P, Wijsenbeek M, Kool M, van den Berge M, Borghuis T, Vaughan A, Corte T, Liu G, Brandsma CA, Gan CT, Olinga P, Timens W, Kahn N, Hansbro PM, Kreuter M, Burgess JK, Melgert BN<\/span> \u2014 DOI: 10.1159\/000547439<\/a><\/div><\/div>
Stabilized Extracellular Vesicle Formulations for Inhalable Dry Powder Development.<\/div>
Jansen EM, van der Koog L, Elferink RAB, Rafie K, Nagelkerke A, Gosens R, Frijlink HW, Hinrichs WLJ<\/span> \u2014 DOI: 10.1002\/smll.202411096<\/a><\/div><\/div><\/div><\/div>\n\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t
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2025<\/h3>
Extracellular Vesicle-Mediated Delivery of Antioxidant Enzymes: Emerging Insights and Translational Opportunities.<\/div>
Wang J, Li Y, Dullaart RPF, Olinga P, Moshage H<\/span> \u2014 DOI: 10.3390\/antiox14121504<\/a><\/div><\/div>
Identification of Subtype-Specific Vulnerabilities in Resistant Glioblastoma: A Computational Pipeline for Biomarkers and Drug Discovery.<\/div>
Lopez-Parra JS, Hameedat F, Sousa SF, Walenkamp AME, Sousa F, A Santos H<\/span> \u2014 DOI: 10.1021\/acs.molpharmaceut.5c01538<\/a><\/div><\/div>
Leucine Protects Dry Powders for Inhalation Against Irreversible Moisture-Induced Aggregation.<\/div>
Jansen EM, van der Koog L, Frijlink HW, Hinrichs WLJ<\/span> \u2014 DOI: 10.3390\/pharmaceutics17111391<\/a><\/div><\/div>
Differential stress responses of immunoisolated human islets embedded in pancreatic extracellular matrix under static and free-fall dynamic conditions.<\/div>
Borges-Silva I, Mantovani MDC, Danh Anh Luu M, Gorter A, Borghuis T, Gasaly N, Cleide Sogayar M, deVos P, Trombetta-Lima M<\/span> \u2014 DOI: 10.1177\/20417314251383295<\/a><\/div><\/div>
The Potential of L. (Thyme) Essential Oil Coating in Preventing Vulvovaginal Candidiasis on Intrauterine Device (IUD) Strings.<\/div>
Sahal G, Donmez HG, Woerdenbag HJ, Taner A, Beksac MS<\/span> \u2014 DOI: 10.3390\/pharmaceutics17101304<\/a><\/div><\/div>
Understanding the impact of excipient variability on oral solid dosage form performance: A possible role for multivariate data analysis, in the form of principal component analysis.<\/div>
Janssen PHM, Dickhoff BHJ, Ferreira A, Gamble J, Shinebaum R, Tobyn M<\/span> \u2014 DOI: 10.1016\/j.xphs.2025.104021<\/a><\/div><\/div>
Placental slice techniques in physiology, pathophysiology, and toxicology: A systematic review with a focus on precision-cut slices.<\/div>
Wang H, Elzinga FA, Nagelkerke A, Touw DJ, Rozendaal F, Hillawie LA, Haan D, Brook B, Gordijn SJ, Prins JR, Olinga P, Mian P<\/span> \u2014 DOI: 10.1016\/j.placenta.2025.09.022<\/a><\/div><\/div>
An In Vitro-In Vivo Comparison of Two Levodopa Dry Powder Products for Inhalation: A Randomized Trial Comparing Inbrija and Levodopa Cyclops.<\/div>
Berends JME, Wimmenhove EJ, Hoppentocht M, Hagedoorn P, Frijlink HW, Grasmeijer F<\/span> \u2014 DOI: 10.3390\/pharmaceutics17091149<\/a><\/div><\/div>
Safety Considerations for Natural Products with Adaptogenic and Immunomodulating Activities.<\/div>
Liang CJW, Woerdenbag HJ, Ekhart C, Vitalone A, van Hunsel FPAM<\/span> \u2014 DOI: 10.3390\/ph18081208<\/a><\/div><\/div>
Extemporaneous Compounding, Pharmacy Preparations and Related Product Care in the Netherlands.<\/div>
Woerdenbag HJ, van Basten B, Oussoren C, Smeets OSNM, Annaciri-Donkers A, Crul M, Maurer JM, Schimmel KJM, Kemper EM, Hooge MNL, Schreuder N, Eikmann M, Ramcharan AS, Lantink RB, Quodbach J, Boersma HH, Kelder O, Larmen\u00e9-Beld KHM, Le Brun PPH, Kok RJ, Schellekens RCA, Breukels O, Frijlink HW, Gareb B<\/span> \u2014 DOI: 10.3390\/pharmaceutics17081005<\/a><\/div><\/div>
Pre-stimulation of precision-cut bovine udder slices with zymosan before LPS exposure indicates aspects of trained immunity especially in the absence of FCS.<\/div>
Filor V, Myslinska J, Saliani A, Dalli J, Olinga P, B\u00e4umer W, Werling D<\/span> \u2014 DOI: 10.1177\/17534259251360484<\/a><\/div><\/div>
Osteoprotegerin Is Elevated in Pulmonary Fibrosis and Associates with Idiopathic Pulmonary Fibrosis Progression: A Pilot Study.<\/div>
Habibie H, Putri KSS, Boorsma CE, Brass DM, Heukels P, Wijsenbeek M, Kool M, van den Berge M, Borghuis T, Vaughan A, Corte T, Liu G, Brandsma CA, Gan CT, Olinga P, Timens W, Kahn N, Hansbro PM, Kreuter M, Burgess JK, Melgert BN<\/span> \u2014 DOI: 10.1159\/000547439<\/a><\/div><\/div>
Corrigendum to "Development of a stable inhalable dry powder formulation with osteoglycin fragment for alveolar epithelial repair" [Int. J. Pharm. 682 (2025) 125913].<\/div>
van der Koog L, Jansen EM, Elferink RAB, Bos SIT, Nagelkerke A, Gosens R, Frijlink HW, Hinrichs WLJ<\/span> \u2014 DOI: 10.1016\/j.ijpharm.2025.125968<\/a><\/div><\/div>
Development of a stable inhalable dry powder formulation with osteoglycin fragment for alveolar epithelial repair.<\/div>
van der Koog L, Jansen EM, Elferink RAB, Bos SIT, Nagelkerke A, Gosens R, Frijlink HW, Hinrichs WLJ<\/span> \u2014 DOI: 10.1016\/j.ijpharm.2025.125913<\/a><\/div><\/div>
Quantifying cross-linking strength in sodium starch glycolate and its impact on tablet disintegration and dissolution.<\/div>
Janssen PHM, Rijpkema W, Stout K, Orbons M, Patel A, Dickhoff BHJ<\/span> \u2014 DOI: 10.1016\/j.ejpb.2025.114803<\/a><\/div><\/div>
The cannabinoid CB receptor: improvement of sleep or memory in rotenone model of Parkinson's disease.<\/div>
Targa ADS, Dos Santos-Lima GZ, Rodrigues LS, Cavalcante SF, Fontenele-Ara\u00fajo J, Torterolo P, Fagotti J, Ilkiw J, Noseda ACD, Trombetta-Lima M, Dorieux F, Dominico PS, Sogayar MC, Andersen ML, Stern CA, Lima MMS<\/span> \u2014 DOI: 10.1016\/j.ejphar.2025.177745<\/a><\/div><\/div>
Correction: van den Born-Bondt et al. Development of an Adaptable Qualification Test Set for Personnel Involved in Visual Inspection Procedures of Parenteral Drug Products Manufactured Under Good Manufacturing Practice Conditions in Hospital Pharmacy Compounding Facilities. 2025, , 74.<\/div>
van den Born-Bondt T, Huizinga HPS, Kappert KR, Westra HH, van Zanten J, Woerdenbag HJ, Maurer JM, Gareb B<\/span> \u2014 DOI: 10.3390\/pharmaceutics17050564<\/a><\/div><\/div>
Therapeutic hyperthermia promotes lipid export and HSP70\/90 during machine perfusion of human livers.<\/div>
Thorne AM, Geng Y, Lantinga VA, Smit M, Kuivenhoven JA, Porte RJ, Kuipers F, Olinga P, Wolters JC, de Meijer VE<\/span> \u2014 DOI: 10.14814\/phy2.70348<\/a><\/div><\/div>
Characterization of Extracellular Vesicles Derived From Human Precision-Cut Liver Slices in Metabolic Dysfunction-Associated Steatotic Liver Disease.<\/div>
Geng Y, Luo K, Stam J, Oosterhuis D, Gorter AR, van den Heuvel M, Crescitelli R, de Meijer VE, Wolters JC, Olinga P<\/span> \u2014 DOI: 10.1002\/jex2.70043<\/a><\/div><\/div>
MicroRNA-26b protects against MASH development in mice and can be efficiently targeted with lipid nanoparticles.<\/div>
Peters L, Rakateli L, Huchzermeier R, Bonnin-Marquez A, Maas SL, Lin C, Jans A, Geng Y, Gorter A, Gijbels M, Rensen S, Olinga P, Hendrikx T, Krawczyk M, Brisbois M, Jankowski J, Bidzhekov K, Weber C, Biessen EAL, Shiri-Sverdlov R, Houben T, D\u00f6ring Y, Bartneck M, van der Vorst E<\/span> \u2014 DOI: 10.7554\/eLife.97165<\/a><\/div><\/div>
Tolerability and Pharmacokinetic Evaluation of Inhaled Dry Powder Tobramycin in Children with Cystic Fibrosis.<\/div>
Akkerman-Nijland AM, Hagedoorn P, Rottier BL, Grasmeijer F, Frijlink HEW, van Luin M, Ter Weijden E, Merkus PJ, Touw DJ, Akkerman OW, Koppelman GH<\/span> \u2014 DOI: 10.3390\/pharmaceutics17030347<\/a><\/div><\/div>
Mechanotransduction and Skeletal Muscle Atrophy: The Interplay Between Focal Adhesions and Oxidative Stress.<\/div>
Kamal KY, Trombetta-Lima M<\/span> \u2014 DOI: 10.3390\/ijms26062802<\/a><\/div><\/div>
Fibroblast-derived osteoglycin promotes epithelial cell repair.<\/div>
van der Koog L, Woest ME, Gorter IC, Verschut V, Elferink RAB, Zuidhof AB, Nugraha DF, Koloko Ngassie ML, Bos SIT, Dhakad D, Wolters JC, Horvatovich PL, Prakash YS, Timens W, Yildirim \u00d6A, Brandsma CA, Frijlink HW, Nagelkerke A, Gosens R<\/span> \u2014 DOI: 10.1038\/s41536-025-00404-3<\/a><\/div><\/div>
Stabilized Extracellular Vesicle Formulations for Inhalable Dry Powder Development.<\/div>
Jansen EM, van der Koog L, Elferink RAB, Rafie K, Nagelkerke A, Gosens R, Frijlink HW, Hinrichs WLJ<\/span> \u2014 DOI: 10.1002\/smll.202411096<\/a><\/div><\/div>
Azithromycin as Host-Directed Therapy for Pulmonary Tuberculosis: A Randomized Pilot Trial.<\/div>
Dekkers BGJ, Kerstjens HAM, Breisnes HW, Leeming DJ, Anthony RM, Frijlink HW, van der Werf TS, Kosterink JGW, Alffenaar JC, Akkerman OW<\/span> \u2014 DOI: 10.1093\/infdis\/jiaf069<\/a><\/div><\/div>
What Is the Optimal Geometry of Dissolving Microneedle Arrays? A Literature Review.<\/div>
Visscher M, Frijlink HW, Hinrichs WLJ<\/span> \u2014 DOI: 10.3390\/pharmaceutics17010124<\/a><\/div><\/div>
Development of an Adaptable Qualification Test Set for Personnel Involved in Visual Inspection Procedures of Parenteral Drug Products Manufactured Under Good Manufacturing Practice Conditions in Hospital Pharmacy Compounding Facilities.<\/div>
van den Born-Bondt T, Huizinga HPS, Kappert KR, Westra HH, van Zanten J, Woerdenbag HJ, Maurer JM, Gareb B<\/span> \u2014 DOI: 10.3390\/pharmaceutics17010074<\/a><\/div><\/div>
Studying the intracellular bile acid concentration and toxicity in drug-induced cholestasis: Comprehensive LC-MS\/MS analysis with human liver slices.<\/div>
Karsten REH, Gier K, de Meijer VE, Huibers WHC, Permentier HP, Verpoorte E, Olinga P<\/span> \u2014 DOI: 10.1016\/j.tiv.2025.106011<\/a><\/div><\/div>
Taylor dispersion analysis and release studies of \u03b2-carotene-loaded PLGA nanoparticles and liposomes in simulated gastrointestinal fluids.<\/div>
Fortunatus RM, Balog S, Sousa F, Vanhecke D, Rothen-Rutishauser B, Taladriz-Blanco P, Petri-Fink A<\/span> \u2014 DOI: 10.1039\/d4ra08138b<\/a><\/div><\/div>
Personalized parathyroid hormone therapy for hypoparathyroidism: Insights from pharmacokinetic-pharmacodynamic modelling.<\/div>
Visscher M, Schuls-Fouchier M, Berends AMA, Muller Kobold AC, Punt NC, Touw DJ<\/span> \u2014 DOI: 10.1111\/bcp.16342<\/a><\/div><\/div>
Qualitative Interviews with Stakeholders in Herbal Pharmacovigilance and Recommendations for Best Practices to be Applied Worldwide.<\/div>
Ekhart C, Wiarda SHP, van de Koppel S, Skalli S, Alghamdi W, Menniti-Ippolito F, Tangchitkhachon K, Mponda JS, Woerdenbag HJ, van Hunsel F<\/span> \u2014 DOI: 10.1007\/s40264-024-01480-y<\/a><\/div><\/div>
The environmental burden of inhalation.<\/div>
de Boer AH<\/span> \u2014 DOI: 10.1016\/j.ejps.2024.106893<\/a><\/div><\/div><\/div><\/div>\n\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t
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Previous Years<\/h3>\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t
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2024<\/h3>
Personalized parathyroid hormone therapy for hypoparathyroidism: Insights from pharmacokinetic-pharmacodynamic modelling.<\/div>
Visscher M, Schuls-Fouchier M, Berends AMA, Muller Kobold AC, Punt NC, Touw DJ<\/span> \u2014 DOI: 10.1111\/bcp.16342<\/a><\/div><\/div>
Analysis of Adverse Reactions Associated with the Use of -Containing Herbal Products.<\/div>
Woerdenbag HJ, Ursidae M, Ekhart C, Schmidt M, Vitalone A, van Hunsel FPAM<\/span> \u2014 DOI: 10.3390\/ph17111490<\/a><\/div><\/div>
Brain organoid models for studying the function of iPSC-derived microglia in neurodegeneration and brain tumours.<\/div>
Sabogal-Guaqueta AM, Mitchell-Garcia T, Hunneman J, Voshart D, Thiruvalluvan A, Foijer F, Kruyt F, Trombetta-Lima M, Eggen BJL, Boddeke E, Barazzuol L, Dolga AM<\/span> \u2014 DOI: 10.1016\/j.nbd.2024.106742<\/a><\/div><\/div>
Precision-cut liver slices as an ex vivo model to assess impaired hepatic glucose production.<\/div>
Kiyuna LA, Krishnamurthy KA, Homan EB, Langelaar-Makkinje M, Gerding A, Bos T, Oosterhuis D, Overduin RJ, Schreuder AB, de Meijer VE, Olinga P, Derks TGJ, van Eunen K, Bakker BM, Oosterveer MH<\/span> \u2014 DOI: 10.1038\/s42003-024-07070-z<\/a><\/div><\/div>
Evaluating the antifibrotic potential of naringenin, asiatic acid, and icariin using murine and human precision-cut liver slices.<\/div>
Luo K, Geng Y, Oosterhuis D, de Meijer VE, Olinga P<\/span> \u2014 DOI: 10.14814\/phy2.16136<\/a><\/div><\/div>
Therapeutic effect of an inhaled levodopa dry powder formulation on off episodes in patients with Parkinson's disease.<\/div>
de Jong L, Luinstra M, Aalbers AF, Wijma-Vos AJ, D'Angremont E, van der Meulen AAE, Rutgers AWF, Steenhuis L, Hagedoorn P, van Laar T, Frijlink HW<\/span> \u2014 DOI: 10.1177\/17562864241289207<\/a><\/div><\/div>
The link between amyloid \u03b2 and ferroptosis pathway in Alzheimer's disease progression.<\/div>
Majern\u00edkov\u00e1 N, Marmolejo-Garza A, Salinas CS, Luu MDA, Zhang Y, Trombetta-Lima M, Tomin T, Birner-Gruenberger R, Lehtonen \u0160, Koistinaho J, Wolters JC, Ayton S, den Dunnen WFA, Dolga AM<\/span> \u2014 DOI: 10.1038\/s41419-024-07152-0<\/a><\/div><\/div>
Real-Time Monitoring of Oxygen-Consumption Rate in Mouse Liver Slices Incubated in Organ-on-a-Chip Devices.<\/div>
Karsten REH, Gier K, Mulder JSH, Grajewski M, Olinga P, Verpoorte E<\/span> \u2014 DOI: 10.1021\/acs.analchem.4c00355<\/a><\/div><\/div>
Inhibition of influenza virus infection in mice by pulmonary administration of a spray dried antiviral drug.<\/div>
Heida R, Jacob Silva PH, Akkerman R, Moser J, de Vries-Idema J, Bornet A, Pawar S, Stellacci F, Frijlink HW, Huckriede ALW, Hinrichs WLJ<\/span> \u2014 DOI: 10.1016\/j.ejpb.2024.114507<\/a><\/div><\/div>
Qualitative Interviews with Stakeholders in Herbal Pharmacovigilance and Recommendations for Best Practices to be Applied Worldwide.<\/div>
Ekhart C, Wiarda SHP, van de Koppel S, Skalli S, Alghamdi W, Menniti-Ippolito F, Tangchitkhachon K, Mponda JS, Woerdenbag HJ, van Hunsel F<\/span> \u2014 DOI: 10.1007\/s40264-024-01480-y<\/a><\/div><\/div>
The environmental burden of inhalation.<\/div>
de Boer AH<\/span> \u2014 DOI: 10.1016\/j.ejps.2024.106893<\/a><\/div><\/div>
Critical review on the role of excipient properties in pharmaceutical powder-to-tablet continuous manufacturing.<\/div>
Janssen PHM, Fathollahi S, Dickhoff BHJ, Frijlink HW<\/span> \u2014 DOI: 10.1080\/17425247.2024.2384698<\/a><\/div><\/div>
Diesel exhaust particles alter mitochondrial bioenergetics and cAMP producing capacity in human bronchial epithelial cells.<\/div>
Cattani-Cavalieri I, Trombetta-Lima M, Yan H, Manzano-Covarrubias AL, Baarsma HA, Oun A, van der Veen MM, Oosterhout E, Dolga AM, Ostrom RS, Valenca SS, Schmidt M<\/span> \u2014 DOI: 10.3389\/ftox.2024.1412864<\/a><\/div><\/div>
Developing Medication Reviews to Improve the Aruban Healthcare System: A Mixed-Methods Pilot Study.<\/div>
Copinga ML, Kok EA, van Dam AJJ, Wever A, Tromp A, Woerdenbag HJ<\/span> \u2014 DOI: 10.3390\/pharmacy12040108<\/a><\/div><\/div>
Fibrogenesis in Human Mucosa and Muscularis Precision-Cut Intestinal Slices.<\/div>
Biel C, Kastermans A, Heidema J, Pehrsson M, Henstra C, Mortensen J, Faber KN, Olinga P<\/span> \u2014 DOI: 10.3390\/cells13131084<\/a><\/div><\/div>
Development and Implementation of an Ultraviolet-Dye-Based Qualification Procedure for Hand Washing and Disinfection to Improve Quality Assurance of Pharmacy Preparations and Compounding, Especially in Cleanrooms: A Pilot Study.<\/div>
Knol CWJ, Stob PH, Woerdenbag HJ<\/span> \u2014 DOI: 10.3390\/pharmacy12030073<\/a><\/div><\/div>
The Therapeutic Potential of Essential Oils in Managing Inflammatory Skin Conditions: A Scoping Review.<\/div>
Dontje AEWK, Schuiling-Veninga CCM, van Hunsel FPAM, Ekhart C, Demirci F, Woerdenbag HJ<\/span> \u2014 DOI: 10.3390\/ph17050571<\/a><\/div><\/div>
Osteoprotegerin is an Early Marker of the Fibrotic Process and of Antifibrotic Treatment Responses in Ex Vivo Lung Fibrosis.<\/div>
Putri KSS, Adhyatmika A, Boorsma CE, Habibie H, Ruigrok MJR, Heukels P, Timens W, de Jager MH, Hinrichs WLJ, Olinga P, Melgert BN<\/span> \u2014 DOI: 10.1007\/s00408-024-00691-5<\/a><\/div><\/div>
Variability in perfusion conditions and set-up parameters used in ex vivo human placenta models: A literature review.<\/div>
Gl\u00e4ttli SC, Elzinga FA, van der Bijl W, Leuvenink HGD, Prins JR, van Goor H, Gordijn SJ, Olinga P, Touw DJ, Mian P<\/span> \u2014 DOI: 10.1016\/j.placenta.2024.03.007<\/a><\/div><\/div>
Metabolic Dysfunction-Associated Steatotic Liver Disease in a Dish: Human Precision-Cut Liver Slices as a Platform for Drug Screening and Interventions.<\/div>
Li M, Larsen FT, van den Heuvel MC, Gier K, Gorter AR, Oosterhuis D, Bijzet J, de Meijer VE, Ravnskjaer K, Nagelkerke A, Olinga P<\/span> \u2014 DOI: 10.3390\/nu16050626<\/a><\/div><\/div>
Combinations of arginine and pullulan reveal the selective effect of stabilization mechanisms on different lyophilized proteins.<\/div>
T T Nguyen K, Zillen D, Lasorsa A, van der Wel PCA, Frijlink HW, L J Hinrichs W<\/span> \u2014 DOI: 10.1016\/j.ijpharm.2024.123938<\/a><\/div><\/div>
Batch vs. continuous direct compression - a comparison of material processability and final tablet quality.<\/div>
Bekaert B, Janssen PHM, Fathollahi S, Vanderroost D, Roelofs T, Dickhoff BHJ, Vervaet C, Vanhoorne V<\/span> \u2014 DOI: 10.1016\/j.ijpx.2023.100226<\/a><\/div><\/div>
Cellular senescence in brain aging and neurodegeneration.<\/div>
Melo Dos Santos LS, Trombetta-Lima M, Eggen B, Demaria M<\/span> \u2014 DOI: 10.1016\/j.arr.2023.102141<\/a><\/div><\/div>
Lipid profile in breast cancer: From signaling pathways to treatment strategies.<\/div>
Taborda Ribas H, Sogayar MC, Dolga AM, Winnischofer SMB, Trombetta-Lima M<\/span> \u2014 DOI: 10.1016\/j.biochi.2023.11.008<\/a><\/div><\/div>
Single cell-resolved study of advanced murine MASH reveals a homeostatic pericyte signaling module.<\/div>
Bendixen SM, Jakobsgaard PR, Hansen D, Hejn KH, Terkelsen MK, Bjerre FA, Thulesen AP, Eriksen NG, Hallenborg P, Geng Y, Dam TV, Larsen FT, Wernberg CW, Vijayathurai J, Scott EAH, Marcher AB, Detlefsen S, Gr\u00f8ntved L, Dimke H, Berdeaux R, de Aguiar Vallim TQ, Olinga P, Lauridsen MM, Krag A, Blagoev B, Ravnskjaer K<\/span> \u2014 DOI: 10.1016\/j.jhep.2023.11.001<\/a><\/div><\/div>
Matrix metalloproteinases in intestinal fibrosis.<\/div>
Biel C, Faber KN, Bank RA, Olinga P<\/span> \u2014 DOI: 10.1093\/ecco-jcc\/jjad178<\/a><\/div><\/div>
Targeted delivery of galunisertib using machine perfusion reduces fibrogenesis in an integrated ex vivo renal transplant and fibrogenesis model.<\/div>
van Leeuwen LL, Ruigrok MJR, Kessler BM, Leuvenink HGD, Olinga P<\/span> \u2014 DOI: 10.1111\/bph.16220<\/a><\/div><\/div>
Clinical Validation of a Capillary Blood Home-Based Self-Sampling Technique for Monitoring of Infliximab, Vedolizumab, and C-Reactive Protein Concentrations in Patients With Inflammatory Bowel Disease.<\/div>
Otten AT, van der Meulen HH, Steenhuis M, Loeff FC, Touw DJ, Kosterink JGW, Frijlink HW, Rispens T, Dijkstra G, Visschedijk MC, Bourgonje AR<\/span> \u2014 DOI: 10.1093\/ibd\/izad103<\/a><\/div><\/div><\/div><\/div>\n\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/details>\n\t\t\t\t\t\t
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2023<\/h3>
Batch vs. continuous direct compression - a comparison of material processability and final tablet quality.<\/div>
Bekaert B, Janssen PHM, Fathollahi S, Vanderroost D, Roelofs T, Dickhoff BHJ, Vervaet C, Vanhoorne V<\/span> \u2014 DOI: 10.1016\/j.ijpx.2023.100226<\/a><\/div><\/div>
Cellular senescence in brain aging and neurodegeneration.<\/div>
Melo Dos Santos LS, Trombetta-Lima M, Eggen B, Demaria M<\/span> \u2014 DOI: 10.1016\/j.arr.2023.102141<\/a><\/div><\/div>
Lubricant Sensitivity of Direct Compression Grades of Lactose in Continuous and Batch Tableting Process.<\/div>
Hebbink GA, Janssen PHM, Kok JH, Menarini L, Giatti F, Funaro C, Consoli SF, Dickhoff BHJ<\/span> \u2014 DOI: 10.3390\/pharmaceutics15112575<\/a><\/div><\/div>
Lipid profile in breast cancer: From signaling pathways to treatment strategies.<\/div>
Taborda Ribas H, Sogayar MC, Dolga AM, Winnischofer SMB, Trombetta-Lima M<\/span> \u2014 DOI: 10.1016\/j.biochi.2023.11.008<\/a><\/div><\/div>
Single cell-resolved study of advanced murine MASH reveals a homeostatic pericyte signaling module.<\/div>
Bendixen SM, Jakobsgaard PR, Hansen D, Hejn KH, Terkelsen MK, Bjerre FA, Thulesen AP, Eriksen NG, Hallenborg P, Geng Y, Dam TV, Larsen FT, Wernberg CW, Vijayathurai J, Scott EAH, Marcher AB, Detlefsen S, Gr\u00f8ntved L, Dimke H, Berdeaux R, de Aguiar Vallim TQ, Olinga P, Lauridsen MM, Krag A, Blagoev B, Ravnskjaer K<\/span> \u2014 DOI: 10.1016\/j.jhep.2023.11.001<\/a><\/div><\/div>
Inhalation of vaccines and antiviral drugs to fight respiratory virus infections: reasons to prioritize the pulmonary route of administration.<\/div>
Heida R, Frijlink HW, Hinrichs WLJ<\/span> \u2014 DOI: 10.1128\/mbio.01295-23<\/a><\/div><\/div>
Surface Engineering Methods for Powder Bed Printed Tablets to Optimize External Smoothness and Facilitate the Application of Different Coatings.<\/div>
Nguyen KTT, Zillen D, van Heijningen FFM, van Bommel KJC, van Ee RJ, Frijlink HW, Hinrichs WLJ<\/span> \u2014 DOI: 10.3390\/pharmaceutics15092193<\/a><\/div><\/div>
Analysis of Safety Concerns on Herbal Products with Assumed Phytoestrogenic Activity.<\/div>
Tjeerdsma AM, van Hunsel FPAM, van de Koppel S, Ekhart C, Vitalone A, Woerdenbag HJ<\/span> \u2014 DOI: 10.3390\/ph16081137<\/a><\/div><\/div>
Efficient fabrication of thermo-stable dissolving microneedle arrays for intradermal delivery of influenza whole inactivated virus vaccine.<\/div>
Lee J, Beukema M, Zaplatynska OA, O'Mahony C, Hinrichs WLJ, Huckriede ALW, Bouwstra JA, van der Maaden K<\/span> \u2014 DOI: 10.1039\/d3bm00377a<\/a><\/div><\/div>
Targeted delivery of galunisertib using machine perfusion reduces fibrogenesis in an integrated ex vivo renal transplant and fibrogenesis model.<\/div>
van Leeuwen LL, Ruigrok MJR, Kessler BM, Leuvenink HGD, Olinga P<\/span> \u2014 DOI: 10.1111\/bph.16220<\/a><\/div><\/div>
Targeting collagen homeostasis for the treatment of liver fibrosis: Opportunities and challenges.<\/div>
Luangmonkong T, Parichatikanond W, Olinga P<\/span> \u2014 DOI: 10.1016\/j.bcp.2023.115740<\/a><\/div><\/div>
Hepatic stellate cells induce an inflammatory phenotype in Kupffer cells via the release of extracellular vesicles.<\/div>
Geng Y, Wang J, Serna-Salas SA, Villanueva AH, Buist-Homan M, Arrese M, Olinga P, Blokzijl H, Moshage H<\/span> \u2014 DOI: 10.1002\/jcp.31086<\/a><\/div><\/div>
Electronic monitoring with a digital smart spacer to support personalized inhaler use education in patients with asthma: The randomized controlled OUTERSPACE trial.<\/div>
Dierick BJH, Achterbosch M, Eikholt AA, Been-Buck S, Klemmeier T, van de Hei SJ, Hagedoorn P, Kerstjens HAM, Kocks JWH, van Boven JFM<\/span> \u2014 DOI: 10.1016\/j.rmed.2023.107376<\/a><\/div><\/div>
Human precision-cut cystic duct and gallbladder slices: a novel method for studying cholangiopathies.<\/div>
Fridrichs J, Hamel B, Kelder W, van den Hoed E, van den Heuvel MC, Hulscher JBF, Olinga P<\/span> \u2014 DOI: 10.3389\/fped.2023.1058319<\/a><\/div><\/div>
Performance Testing of a Homemade Aerosol Generator for Pulmonary Administration of Dry Powder Formulations to Mice.<\/div>
Heida R, Hagedoorn P, van Meel MC, Prins JER, Simonis FS, Akkerman R, Huckriede ALW, Frijlink HW, de Boer AH, Hinrichs WLJ<\/span> \u2014 DOI: 10.3390\/pharmaceutics15071847<\/a><\/div><\/div>
Placenta-on-a-Chip as an In Vitro Approach to Evaluate the Physiological and Structural Characteristics of the Human Placental Barrier upon Drug Exposure: A Systematic Review.<\/div>
Elzinga FA, Khalili B, Touw DJ, Prins JR, Olinga P, Leuvenink HGD, van Goor H, Gordijn SJ, Nagelkerke A, Mian P<\/span> \u2014 DOI: 10.3390\/jcm12134315<\/a><\/div><\/div>
Standardized Protocol for the Preparation of Precision-Cut Kidney Slices: A Translational Model of Renal Fibrosis.<\/div>
Jensen MS, Merrild C, N\u00f8rregaard R, Olinga P, Mutsaers HAM<\/span> \u2014 DOI: 10.1007\/978-1-0716-3179-9_9<\/a><\/div><\/div>
Nebulization of PEGylated recombinant human deoxyribonuclease I using vibrating membrane nebulizers: A technical feasibility study.<\/div>
Mahri S, Wilms T, Hagedorm P, Guichard MJ, Vanvarenberg K, Dumoulin M, Frijlink H, Vanbever R<\/span> \u2014 DOI: 10.1016\/j.ejps.2023.106522<\/a><\/div><\/div>
Capsules with Ileocolonic-Targeted Release of Vitamin B, B, and C (ColoVit) Intended for Optimization of Gut Health: Development and Validation of the Production Process.<\/div>
Ahmed AA, Otten AT, Gareb B, Huijmans JE, Eissens AC, Rehman A, Dijkstra G, Kosterink JGW, Frijlink HW, Schellekens RCA<\/span> \u2014 DOI: 10.3390\/pharmaceutics15051354<\/a><\/div><\/div>
Transcriptomic profiling of induced steatosis in human and mouse precision-cut liver slices.<\/div>
Simon E, Motyka M, Prins GH, Li M, Rust W, Kauschke S, Viollet C, Olinga P, Oldenburger A<\/span> \u2014 DOI: 10.1038\/s41597-023-02220-0<\/a><\/div><\/div>
Potential, Limitations and Risks of Cannabis-Derived Products in Cancer Treatment.<\/div>
Woerdenbag HJ, Olinga P, Kok EA, Brugman DAP, van Ark UF, Ramcharan AS, Lebbink PW, Hoogwater FJH, Knapen DG, de Groot DJA, Nijkamp MW<\/span> \u2014 DOI: 10.3390\/cancers15072119<\/a><\/div><\/div>
Development of an inhalable antiviral powder formulation against respiratory syncytial virus.<\/div>
Heida R, Akkerman R, Jacob Silva PH, Lakerveld AJ, Ortiz D, Bigogno C, Gasbarri M, van Kasteren PB, Stellacci F, Frijlink HW, Huckriede ALW, Hinrichs WLJ<\/span> \u2014 DOI: 10.1016\/j.jconrel.2023.03.059<\/a><\/div><\/div>
Designing Formulation Strategies for Enhanced Stability of Therapeutic Peptides in Aqueous Solutions: A Review.<\/div>
Nugrahadi PP, Hinrichs WLJ, Frijlink HW, Sch\u00f6neich C, Avanti C<\/span> \u2014 DOI: 10.3390\/pharmaceutics15030935<\/a><\/div><\/div>
Effects of ileocolonic delivered vitamin B, B and C (ColoVit) or the Groningen anti-inflammatory diet on disease course and microbiome of patients with Crohn's disease (VITA-GrAID study): a protocol for a randomised and partially blinded trial.<\/div>
Otten AT, Peters V, Barth I, Stevens CL, Bourgonje AR, Frijlink HW, Harmsen HJM, Rehman A, Campmans-Kuijpers MJE, Dijkstra G<\/span> \u2014 DOI: 10.1136\/bmjopen-2022-069654<\/a><\/div><\/div>
Smart Specification Setting for Dry Powder Inhalation Carriers.<\/div>
Janssen PHM, Bastiaansen M, Buijvoets LB, Frijlink HW<\/span> \u2014 DOI: 10.1016\/j.xphs.2023.02.018<\/a><\/div><\/div>
A Single Injection with Sustained-Release Microspheres and a Prime-Boost Injection of Bovine Serum Albumin Elicit the Same IgG Antibody Response in Mice.<\/div>
van der Kooij RS, Beukema M, Huckriede ALW, Zuidema J, Steendam R, Frijlink HW, Hinrichs WLJ<\/span> \u2014 DOI: 10.3390\/pharmaceutics15020676<\/a><\/div><\/div>
Restoration of Bile Duct Injury of Donor Livers During Ex Situ Normothermic Machine Perfusion.<\/div>
de Jong IEM, Bodewes SB, van Leeuwen OB, Oosterhuis D, Lantinga VA, Thorne AM, Lascaris B, van den Heuvel MC, Wells RG, Olinga P, de Meijer VE, Porte RJ<\/span> \u2014 DOI: 10.1097\/TP.0000000000004531<\/a><\/div><\/div>
Hepatoprotective Efficacy of Cycloastragenol Alleviated the Progression of Liver Fibrosis in Carbon-Tetrachloride-Treated Mice.<\/div>
Luangmonkong T, Puphancharoensuk P, Tongsongsang V, Olinga P, Parichatikanond W<\/span> \u2014 DOI: 10.3390\/biomedicines11010231<\/a><\/div><\/div>
Differential effects of oleate on vascular endothelial and liver sinusoidal endothelial cells reveal its toxic features in vitro.<\/div>
Geng Y, Arroyave-Ospina JC, Buist-Homan M, Plantinga J, Olinga P, Reijngoud DJ, Van Vilsteren FGI, Blokzijl H, Kamps JAAM, Moshage H<\/span> \u2014 DOI: 10.1016\/j.jnutbio.2022.109255<\/a><\/div><\/div>
Safety assessment and adverse drug reaction reporting of tea tree oil (Melaleuca aetheroleum).<\/div>
Bekhof AMW, van Hunsel FPAM, van de Koppel S, Woerdenbag HJ<\/span> \u2014 DOI: 10.1002\/ptr.7687<\/a><\/div><\/div><\/div><\/div>\n\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/details>\n\t\t\t\t\t\t
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2022<\/h3>
Safety assessment and adverse drug reaction reporting of tea tree oil (Melaleuca aetheroleum).<\/div>
Bekhof AMW, van Hunsel FPAM, van de Koppel S, Woerdenbag HJ<\/span> \u2014 DOI: 10.1002\/ptr.7687<\/a><\/div><\/div>
RANKL confers protection against cell death in precision-cut lung slices.<\/div>
Ruigrok MJR, Roest MAP, Frijlink HW, Olinga P, Hinrichs WLJ, Melgert BN<\/span> \u2014 DOI: 10.3389\/fphys.2022.1029697<\/a><\/div><\/div>
Are inhaled mRNA vaccines safe and effective? A review of preclinical studies.<\/div>
Jansen EM, Frijlink HW, Hinrichs WL, Ruigrok MJ<\/span> \u2014 DOI: 10.1080\/17425247.2022.2131767<\/a><\/div><\/div>
Formulation of a 3D Printed Biopharmaceutical: The Development of an Alkaline Phosphatase Containing Tablet with Ileo-Colonic Release Profile to Treat Ulcerative Colitis.<\/div>
Nguyen KTT, Heijningen FFM, Zillen D, van Bommel KJC, van Ee RJ, Frijlink HW, Hinrichs WLJ<\/span> \u2014 DOI: 10.3390\/pharmaceutics14102179<\/a><\/div><\/div>
The impact of lactose type on disintegration: An integral study on porosity and polymorphism.<\/div>
Janssen PHM, Berardi A, Kok JH, Thornton AW, Dickhoff BHJ<\/span> \u2014 DOI: 10.1016\/j.ejpb.2022.10.012<\/a><\/div><\/div>
The Development and Implementation of Airflow Visualization Studies ("Smoke" Studies) as a Training Tool in Aseptic Hospital Compounding Facilities.<\/div>
Borgonje PE, Wibier L, Noordman P, Woerdenbag HJ, Gareb B<\/span> \u2014 DOI: 10.3390\/pharmacy10050101<\/a><\/div><\/div>
Dry powder inhalation, part 2: the present and future.<\/div>
de Boer AH, Hagedoorn P, Grasmeijer F<\/span> \u2014 DOI: 10.1080\/17425247.2022.2112570<\/a><\/div><\/div>
Dry powder inhalation, part 1: ancient history and precursors to modern dry powder inhalers.<\/div>
de Boer AH, Hagedoorn P, Grasmeijer F<\/span> \u2014 DOI: 10.1080\/17425247.2022.2112568<\/a><\/div><\/div>
Verteporfin ameliorates fibrotic aspects of Dupuytren's disease nodular fibroblasts irrespective the activation state of the cells.<\/div>
Puerta Cavanzo N, Riesmeijer SA, Holt-Kedde IL, Werker PMN, Piersma B, Olinga P, Bank RA<\/span> \u2014 DOI: 10.1038\/s41598-022-18116-9<\/a><\/div><\/div>
Pharmacology, particle deposition and drug administration techniques of intranasal corticosteroids for treating allergic rhinitis.<\/div>
Rollema C, van Roon EN, van Boven JFM, Hagedoorn P, Klemmeier T, Kocks JH, Metting EI, Oude Elberink HNG, Peters TTA, San Giorgi MRM, de Vries TW<\/span> \u2014 DOI: 10.1111\/cea.14212<\/a><\/div><\/div>
Digital spacer data driven COPD inhaler adherence education: The OUTERSPACE proof-of-concept study.<\/div>
Dierick BJH, Been-Buck S, Klemmeier T, Hagedoorn P, van de Hei SJ, Kerstjens HAM, Kocks JWH, Zijp TR, Wessels AMA, Touw DJ, van Boven JFM<\/span> \u2014 DOI: 10.1016\/j.rmed.2022.106940<\/a><\/div><\/div>
Tolerability and pharmacokinetic evaluation of inhaled dry powder hydroxychloroquine in healthy volunteers.<\/div>
de Reus YA, Hagedoorn P, Sturkenboom MGG, Grasmeijer F, Bolhuis MS, Sibum I, Kerstjens HAM, Frijlink HW, Akkerman OW<\/span> \u2014 DOI: 10.1371\/journal.pone.0272034<\/a><\/div><\/div>
Assessing the Immunomodulatory Effect of Size on the Uptake and Immunogenicity of Influenza- and Hepatitis B Subunit Vaccines In Vitro.<\/div>
Heida R, Born PA, Tapia-Calle G, Frijlink HW, Salvati A, Huckriede ALW, Hinrichs WLJ<\/span> \u2014 DOI: 10.3390\/ph15070887<\/a><\/div><\/div>
Distinct responses between healthy and cirrhotic human livers upon lipopolysaccharide challenge: possible implications for acute-on-chronic liver failure.<\/div>
Suriguga S, Li M, Luangmonkong T, Boersema M, de Jong KP, Oosterhuis D, Gorter AR, Beljaars L, Olinga P<\/span> \u2014 DOI: 10.1152\/ajpgi.00243.2021<\/a><\/div><\/div>
Mouse precision-cut liver slices as an ex vivo model to study drug-induced cholestasis.<\/div>
Karsten REH, Krijnen NJW, Maho W, Permentier H, Verpoorte E, Olinga P<\/span> \u2014 DOI: 10.1007\/s00204-022-03321-2<\/a><\/div><\/div>
Turning green: the impact of changing to more eco-friendly respiratory healthcare - a carbon and cost analysis of Dutch prescription data.<\/div>
Ten Have P, van Hal P, Wichers I, Kooistra J, Hagedoorn P, Brakema EA, Chavannes N, de Heer P, Ossebaard HC<\/span> \u2014 DOI: 10.1136\/bmjopen-2021-055546<\/a><\/div><\/div>
Can electronic monitoring with a digital smart spacer support personalised medication adherence and inhaler technique education in patients with asthma?: Protocol of the randomised controlled OUTERSPACE trial.<\/div>
Dierick BHJ, Achterbosch M, Been-Buck S, Klemmeier T, van de Hei SJ, Hagedoorn P, Kerstjens HAM, Kocks JWH, van Boven JFM<\/span> \u2014 DOI: 10.1136\/bmjopen-2021-059929<\/a><\/div><\/div>
Analysis of Reports on Adverse Drug Reactions Related to Herbal Medicinal Products and Herbal Supplements in the Netherlands Received by the National Pharmacovigilance Centre Lareb.<\/div>
van Hunsel FPAM, van der Kooi D, van de Koppel S, Kroes BH, Woerdenbag HJ<\/span> \u2014 DOI: 10.1007\/s40264-022-01180-5<\/a><\/div><\/div>
The effect of excipient particle size on the reduction of compactibility after roller compaction.<\/div>
Janssen PHM, Jaspers M, Meier R, Roelofs TP, Dickhoff BHJ<\/span> \u2014 DOI: 10.1016\/j.ijpx.2022.100117<\/a><\/div><\/div>
Extending the viability of human precision-cut intestinal slice model for drug metabolism studies.<\/div>
Biel C, Martinec O, Sibering B, van Summeren K, Wessels AMA, Touw DJ, de Jong KP, de Meijer VE, Faber KN, Klooster JPT, de Graaf IAM, Olinga P<\/span> \u2014 DOI: 10.1007\/s00204-022-03295-1<\/a><\/div><\/div>
Performance of Tablet Splitters, Crushers, and Grinders in Relation to Personalised Medication with Tablets.<\/div>
Woerdenbag HJ, Visser JC, Leferink Op Reinink MPAM, van Orsoy RR, Eissens AC, Hagedoorn P, Dijkstra H, Allersma DP, Ng SW, Smeets OSNM, Frijlink HW<\/span> \u2014 DOI: 10.3390\/pharmaceutics14020320<\/a><\/div><\/div>
Intradermal Administration of Influenza Vaccine with Trehalose and Pullulan-Based Dissolving Microneedle Arrays.<\/div>
Tian Y, Lee J, van der Maaden K, Bhide Y, de Vries-Idema JJ, Akkerman R, O'Mahony C, Jiskoot W, Frijlink HW, Huckriede ALW, Hinrichs WLJ, Bouwstra JA, Beukema M<\/span> \u2014 DOI: 10.1016\/j.xphs.2022.01.033<\/a><\/div><\/div>
Shifting Paradigms for Suppressing Fibrosis in Kidney Transplants: Supplementing Perfusion Solutions With Anti-fibrotic Drugs.<\/div>
van Leeuwen LL, Leuvenink HGD, Olinga P, Ruigrok MJR<\/span> \u2014 DOI: 10.3389\/fmed.2021.806774<\/a><\/div><\/div>
Osteoprotegerin Expression in Liver is Induced by IL13 through TGF\u03b2.<\/div>
Adhyatmika A, Putri KSS, Gore E, Mangnus KA, Reker-Smit C, Schuppan D, Beljaars L, Olinga P, Melgert BN<\/span> \u2014 DOI: 10.33594\/000000492<\/a><\/div><\/div>
An overview of the production methods for core-shell microspheres for parenteral controlled drug delivery.<\/div>
van der Kooij RS, Steendam R, Frijlink HW, Hinrichs WLJ<\/span> \u2014 DOI: 10.1016\/j.ejpb.2021.11.007<\/a><\/div><\/div>
New Therapeutic Approach for Intestinal Fibrosis Through Inhibition of pH-Sensing Receptor GPR4.<\/div>
Weder B, Schefer F, van Haaften WT, Patsenker E, Stickel F, Mueller S, Hutter S, Schuler C, Baebler K, Wang Y, Mamie C, Dijkstra G, de Valli\u00e8re C, Imenez Silva PH, Wagner CA, Frey-Wagner I, Ruiz PA, Seuwen K, Rogler G, Hausmann M<\/span> \u2014 DOI: 10.1093\/ibd\/izab140<\/a><\/div><\/div>
Inhaled vaccine delivery in the combat against respiratory viruses: a 2021 overview of recent developments and implications for COVID-19.<\/div>
Heida R, Hinrichs WL, Frijlink HW<\/span> \u2014 DOI: 10.1080\/14760584.2021.1903878<\/a><\/div><\/div>
Science- and risk-based strategy to qualify prefillable autoclavable syringes as primary packaging material.<\/div>
Larmen\u00e9-Beld K, Wijnsma R, Kuiper A, van Berkel S, Robben H, Taxis K, Frijlink H<\/span> \u2014 DOI: 10.1136\/ejhpharm-2020-002333<\/a><\/div><\/div><\/div><\/div>\n\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/details>\n\t\t\t\t\t\t
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2021<\/h3>
Shifting Paradigms for Suppressing Fibrosis in Kidney Transplants: Supplementing Perfusion Solutions With Anti-fibrotic Drugs.<\/div>
van Leeuwen LL, Leuvenink HGD, Olinga P, Ruigrok MJR<\/span> \u2014 DOI: 10.3389\/fmed.2021.806774<\/a><\/div><\/div>
The Effects of Butyrate on Induced Metabolic-Associated Fatty Liver Disease in Precision-Cut Liver Slices.<\/div>
Prins GH, Rios-Morales M, Gerding A, Reijngoud DJ, Olinga P, Bakker BM<\/span> \u2014 DOI: 10.3390\/nu13124203<\/a><\/div><\/div>
Formulation and In Vitro Evaluation of Pellets Containing Sulfasalazine and Caffeine to Verify Ileo-Colonic Drug Delivery.<\/div>
Broesder A, Bircan SY, de Waard AB, Eissens AC, Frijlink HW, Hinrichs WLJ<\/span> \u2014 DOI: 10.3390\/pharmaceutics13121985<\/a><\/div><\/div>
An overview of the production methods for core-shell microspheres for parenteral controlled drug delivery.<\/div>
van der Kooij RS, Steendam R, Frijlink HW, Hinrichs WLJ<\/span> \u2014 DOI: 10.1016\/j.ejpb.2021.11.007<\/a><\/div><\/div>
Microfluidic Production of Polymeric Core-Shell Microspheres for the Delayed Pulsatile Release of Bovine Serum Albumin as a Model Antigen.<\/div>
van der Kooij RS, Steendam R, Zuidema J, Frijlink HW, Hinrichs WLJ<\/span> \u2014 DOI: 10.3390\/pharmaceutics13111854<\/a><\/div><\/div>
Editorial: Organ Fibrosis: Pathogenesis, Biomarkers and Therapeutic Targets.<\/div>
Mutsaers HAM, N\u00f8rregaard R, Olinga P<\/span> \u2014 DOI: 10.3389\/fmed.2021.793507<\/a><\/div><\/div>
The gastrointestinal microbiota in colorectal cancer cell migration and invasion.<\/div>
Henstra C, van Praagh J, Olinga P, Nagelkerke A<\/span> \u2014 DOI: 10.1007\/s10585-021-10130-x<\/a><\/div><\/div>
Hepatic Steatosis Contributes to the Development of Muscle Atrophy Inter-Organ Crosstalk.<\/div>
Pasmans K, Adriaens ME, Olinga P, Langen R, Rensen SS, Schaap FG, Olde Damink SWM, Caiment F, van Loon LJC, Blaak EE, Meex RCR<\/span> \u2014 DOI: 10.3389\/fendo.2021.733625<\/a><\/div><\/div>
Local Inhibition of Indoleamine 2,3-Dioxygenase Mitigates Renal Fibrosis.<\/div>
Jensen CG, Jensen MS, Tingskov SJ, Olinga P, N\u00f8rregaard R, Mutsaers HAM<\/span> \u2014 DOI: 10.3390\/biomedicines9080856<\/a><\/div><\/div>
An Organogold Compound as Potential Antimicrobial Agent against Drug-Resistant Bacteria: Initial Mechanistic Insights.<\/div>
Chakraborty P, Oosterhuis D, Bonsignore R, Casini A, Olinga P, Scheffers DJ<\/span> \u2014 DOI: 10.1002\/cmdc.202100342<\/a><\/div><\/div>
Rifampicin Induces Gene, Protein, and Activity of P-Glycoprotein (ABCB1) in Human Precision-Cut Intestinal Slices.<\/div>
Martinec O, Biel C, de Graaf IAM, Huliciak M, de Jong KP, Staud F, Cecka F, Olinga P, Vokral I, Cerveny L<\/span> \u2014 DOI: 10.3389\/fphar.2021.684156<\/a><\/div><\/div>
Use of Precision-Cut Tissue Slices as a Translational Model to Study Host-Pathogen Interaction.<\/div>
Majorova D, Atkins E, Martineau H, Vokral I, Oosterhuis D, Olinga P, Wren B, Cuccui J, Werling D<\/span> \u2014 DOI: 10.3389\/fvets.2021.686088<\/a><\/div><\/div>
Educational Video Improves Knowledge about Outpatients' Usage of Antibiotics in Two Public Hospitals in Indonesia.<\/div>
Herawati F, Yulia R, Arifin B, Frasetyo I, Setiasih , Woerdenbag HJ, Avanti C, Andrajati R<\/span> \u2014 DOI: 10.3390\/antibiotics10050606<\/a><\/div><\/div>
Ileo-Colon Targeting of the Poorly Water-Soluble Drug Celecoxib Using a pH-Dependent Coating in Combination with Self-Emulsifying Drug Delivery or Solid Dispersion Systems.<\/div>
Broesder A, Berends JME, Scheepers SM, Nguyen DN, Frijlink HW, Hinrichs WLJ<\/span> \u2014 DOI: 10.3390\/pharmaceutics13050731<\/a><\/div><\/div>
Isocratic high-performance liquid chromatography (HPLC) for simultaneous quantification of curcumin and piperine in a microparticle formulation containing and .<\/div>
Setyaningsih D, Santoso YA, Hartini YS, Murti YB, Hinrichs WLJ, Patramurti C<\/span> \u2014 DOI: 10.1016\/j.heliyon.2021.e06541<\/a><\/div><\/div>
Biofilm Formation Assay on Essential Oil Coated Silicone Rubber.<\/div>
Sahal G, Woerdenbag HJ, Hinrichs WLJ, Visser A, van der Mei HC, Bilkay IS<\/span> \u2014 DOI: 10.21769\/BioProtoc.3941<\/a><\/div><\/div>
Colorectal anastomotic leak: transcriptomic profile analysis.<\/div>
van Praagh JB, de Wit JG, Olinga P, de Haan JJ, Nagengast WB, Fehrmann RSN, Havenga K<\/span> \u2014 DOI: 10.1093\/bjs\/znaa066<\/a><\/div><\/div>
Inhaled vaccine delivery in the combat against respiratory viruses: a 2021 overview of recent developments and implications for COVID-19.<\/div>
Heida R, Hinrichs WL, Frijlink HW<\/span> \u2014 DOI: 10.1080\/14760584.2021.1903878<\/a><\/div><\/div>
Legislation and current developments in adverse drug reaction reporting in Mongolia: how far are we?<\/div>
Zulzaga Z, Myagmarsuren E, Woerdenbag HJ, van Puijenbroek EP<\/span> \u2014 DOI: 10.1186\/s40545-021-00298-8<\/a><\/div><\/div>
Silencing Heat Shock Protein 47 (HSP47) in Fibrogenic Precision-Cut Lung Slices: A Surprising Lack of Effects on Fibrogenesis?<\/div>
Ruigrok MJR, El Amasi KEM, Leeming DJ, Sand JMB, Frijlink HW, Hinrichs WLJ, Olinga P<\/span> \u2014 DOI: 10.3389\/fmed.2021.607962<\/a><\/div><\/div>
Gene therapy strategies for idiopathic pulmonary fibrosis: recent advances, current challenges, and future directions.<\/div>
Ruigrok MJR, Frijlink HW, Melgert BN, Olinga P, Hinrichs WLJ<\/span> \u2014 DOI: 10.1016\/j.omtm.2021.01.003<\/a><\/div><\/div>
Nanoparticle-induced inflammation and fibrosis in ex vivo murine precision-cut liver slices and effects of nanoparticle exposure conditions.<\/div>
Bartucci R, van der Meer AZ, Boersma YL, Olinga P, Salvati A<\/span> \u2014 DOI: 10.1007\/s00204-021-02992-7<\/a><\/div><\/div>
Non-Toxic Virucidal Macromolecules Show High Efficacy Against Influenza Virus Ex Vivo and In Vivo.<\/div>
Kocabiyik O, Cagno V, Silva PJ, Zhu Y, Sedano L, Bhide Y, Mettier J, Medaglia C, Da Costa B, Constant S, Huang S, Kaiser L, Hinrichs WLJ, Huckriede A, Le Goffic R, Tapparel C, Stellacci F<\/span> \u2014 DOI: 10.1002\/advs.202001012<\/a><\/div><\/div>
Macromolecular Crowding as a Tool to Screen Anti-fibrotic Drugs: The Scar-in-a-Jar System Revisited.<\/div>
Puerta Cavanzo N, Bigaeva E, Boersema M, Olinga P, Bank RA<\/span> \u2014 DOI: 10.3389\/fmed.2020.615774<\/a><\/div><\/div>
Science- and risk-based strategy to qualify prefillable autoclavable syringes as primary packaging material.<\/div>
Larmen\u00e9-Beld K, Wijnsma R, Kuiper A, van Berkel S, Robben H, Taxis K, Frijlink H<\/span> \u2014 DOI: 10.1136\/ejhpharm-2020-002333<\/a><\/div><\/div>
Collagen release by human hepatic stellate cells requires vitamin C and is efficiently blocked by hydroxylase inhibition.<\/div>
Smith-Cortinez N, Fagundes RR, Gomez V, Kong D, de Waart DR, Heegsma J, Sydor S, Olinga P, de Meijer VE, Taylor CT, Bank R, Paulusma CC, Faber KN<\/span> \u2014 DOI: 10.1096\/fj.202001564RR<\/a><\/div><\/div>
The pharmacokinetics of antibiotics in cystic fibrosis.<\/div>
Akkerman-Nijland AM, Akkerman OW, Grasmeijer F, Hagedoorn P, Frijlink HW, Rottier BL, Koppelman GH, Touw DJ<\/span> \u2014 DOI: 10.1080\/17425255.2021.1836157<\/a><\/div><\/div>
Advances in the development of entry inhibitors for sialic-acid-targeting viruses.<\/div>
Heida R, Bhide YC, Gasbarri M, Kocabiyik \u00d6, Stellacci F, Huckriede ALW, Hinrichs WLJ, Frijlink HW<\/span> \u2014 DOI: 10.1016\/j.drudis.2020.10.009<\/a><\/div><\/div>
The Citrullinated and MMP-degraded Vimentin Biomarker (VICM) Predicts Early Response to Anti-TNF\u03b1 Treatment in Crohn's Disease.<\/div>
Mortensen JH, van Haaften WT, Karsdal MA, Bay-Jensen AC, Olinga P, Gr\u00f8nb\u00e6k H, Hvas CL, Manon-Jensen T, Dijkstra G, Dige A<\/span> \u2014 DOI: 10.1097\/MCG.0000000000001341<\/a><\/div><\/div><\/div><\/div>\n\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/details>\n\t\t\t\t\t\t
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2020<\/h3>
Non-Toxic Virucidal Macromolecules Show High Efficacy Against Influenza Virus Ex Vivo and In Vivo.<\/div>
Kocabiyik O, Cagno V, Silva PJ, Zhu Y, Sedano L, Bhide Y, Mettier J, Medaglia C, Da Costa B, Constant S, Huang S, Kaiser L, Hinrichs WLJ, Huckriede A, Le Goffic R, Tapparel C, Stellacci F<\/span> \u2014 DOI: 10.1002\/advs.202001012<\/a><\/div><\/div>
Macromolecular Crowding as a Tool to Screen Anti-fibrotic Drugs: The Scar-in-a-Jar System Revisited.<\/div>
Puerta Cavanzo N, Bigaeva E, Boersema M, Olinga P, Bank RA<\/span> \u2014 DOI: 10.3389\/fmed.2020.615774<\/a><\/div><\/div>
Current Concepts of Biliary Atresia and Matrix Metalloproteinase-7: A Review of Literature.<\/div>
Nomden M, Beljaars L, Verkade HJ, Hulscher JBF, Olinga P<\/span> \u2014 DOI: 10.3389\/fmed.2020.617261<\/a><\/div><\/div>
Collagen release by human hepatic stellate cells requires vitamin C and is efficiently blocked by hydroxylase inhibition.<\/div>
Smith-Cortinez N, Fagundes RR, Gomez V, Kong D, de Waart DR, Heegsma J, Sydor S, Olinga P, de Meijer VE, Taylor CT, Bank R, Paulusma CC, Faber KN<\/span> \u2014 DOI: 10.1096\/fj.202001564RR<\/a><\/div><\/div>
The pharmacokinetics of antibiotics in cystic fibrosis.<\/div>
Akkerman-Nijland AM, Akkerman OW, Grasmeijer F, Hagedoorn P, Frijlink HW, Rottier BL, Koppelman GH, Touw DJ<\/span> \u2014 DOI: 10.1080\/17425255.2021.1836157<\/a><\/div><\/div>
Advances in the development of entry inhibitors for sialic-acid-targeting viruses.<\/div>
Heida R, Bhide YC, Gasbarri M, Kocabiyik \u00d6, Stellacci F, Huckriede ALW, Hinrichs WLJ, Frijlink HW<\/span> \u2014 DOI: 10.1016\/j.drudis.2020.10.009<\/a><\/div><\/div>
Serological Biomarkers of Tissue Turnover Identify Responders to Anti-TNF Therapy in Crohn's Disease: A Pilot Study.<\/div>
van Haaften WT, Mortensen JH, Dige AK, Gr\u00f8nb\u00e6k H, Hvas CL, Bay-Jensen AC, Karsdal MA, Olinga P, Manon-Jensen T, Dijkstra G<\/span> \u2014 DOI: 10.14309\/ctg.0000000000000217<\/a><\/div><\/div>
Colistin dry powder inhalation with the Twincer\u2122: An effective and more patient friendly alternative to nebulization.<\/div>
Akkerman-Nijland AM, Grasmeijer F, Kerstjens HAM, Frijlink HW, van der Vaart H, Vonk JM, Hagedoorn P, Rottier BL, Koppelman GH, Akkerman OW<\/span> \u2014 DOI: 10.1371\/journal.pone.0239658<\/a><\/div><\/div>
Intestinal stenosis in Crohn's disease shows a generalized upregulation of genes involved in collagen metabolism and recognition that could serve as novel anti-fibrotic drug targets.<\/div>
van Haaften WT, Blokzijl T, Hofker HS, Olinga P, Dijkstra G, Bank RA, Boersema M<\/span> \u2014 DOI: 10.1177\/1756284820952578<\/a><\/div><\/div>
Prefilled Cyclic Olefin Sterilized Syringes of Norepinephrine Injection Solution Do Not Need to Be Stabilized by Antioxidants.<\/div>
Larmen\u00e9-Beld KHM, van Berkel S, Wijnsma R, Taxis K, Frijlink HW<\/span> \u2014 DOI: 10.1208\/s12249-020-01784-z<\/a><\/div><\/div>
Survival and cellular heterogeneity of epithelium in cultured mouse and rat precision-cut intestinal slices.<\/div>
Biel C, Bigaeva E, Hesse M, Bomers JJM, van Summeren K, Teunis MAT, Vaessen S, Ten Klooster JP, Olinga P<\/span> \u2014 DOI: 10.1016\/j.tiv.2020.104974<\/a><\/div><\/div>
Automated Filling Equipment Allows Increase in the Maximum Dose to Be Filled in the Cyclops High Dose Dry Powder Inhalation Device While Maintaining Dispersibility.<\/div>
Sibum I, Hagedoorn P, Botterman CO, Frijlink HW, Grasmeijer F<\/span> \u2014 DOI: 10.3390\/pharmaceutics12070645<\/a><\/div><\/div>
Host microbiota dictates the proinflammatory impact of LPS in the murine liver.<\/div>
Suriguga S, Luangmonkong T, Mutsaers HAM, Groothuis GMM, Olinga P<\/span> \u2014 DOI: 10.1016\/j.tiv.2020.104920<\/a><\/div><\/div>
pH-dependent ileocolonic drug delivery, part II: preclinical evaluation of novel drugs and novel excipients.<\/div>
Broesder A, Kosta AMAC, Woerdenbag HJ, Nguyen DN, Frijlink HW, Hinrichs WLJ<\/span> \u2014 DOI: 10.1016\/j.drudis.2020.06.012<\/a><\/div><\/div>
pH-dependent ileocolonic drug delivery, part I: in vitro and clinical evaluation of novel systems.<\/div>
Broesder A, Woerdenbag HJ, Prins GH, Nguyen DN, Frijlink HW, Hinrichs WLJ<\/span> \u2014 DOI: 10.1016\/j.drudis.2020.06.011<\/a><\/div><\/div>
Review: Local Tumor Necrosis Factor-\u03b1 Inhibition in Inflammatory Bowel Disease.<\/div>
Gareb B, Otten AT, Frijlink HW, Dijkstra G, Kosterink JGW<\/span> \u2014 DOI: 10.3390\/pharmaceutics12060539<\/a><\/div><\/div>
Comparative study of nanoparticle uptake and impact in murine lung, liver and kidney tissue slices.<\/div>
Bartucci R, Paramanandana A, Boersma YL, Olinga P, Salvati A<\/span> \u2014 DOI: 10.1080\/17435390.2020.1771785<\/a><\/div><\/div>
Osteoprotegerin is More than a Possible Serum Marker in Liver Fibrosis: A Study into its Function in Human and Murine Liver.<\/div>
Adhyatmika A, Beljaars L, Putri KSS, Habibie H, Boorsma CE, Reker-Smit C, Luangmonkong T, Guney B, Haak A, Mangnus KA, Post E, Poelstra K, Ravnskjaer K, Olinga P, Melgert BN<\/span> \u2014 DOI: 10.3390\/pharmaceutics12050471<\/a><\/div><\/div>
Predictive Value of Precision-Cut Kidney Slices as an Ex Vivo Screening Platform for Therapeutics in Human Renal Fibrosis.<\/div>
Bigaeva E, Puerta Cavanzo N, Stribos EGD, de Jong AJ, Biel C, Mutsaers HAM, Jensen MS, N\u00f8rregaard R, Leliveld AM, de Jong IJ, Hillebrands JL, van Goor H, Boersema M, Bank RA, Olinga P<\/span> \u2014 DOI: 10.3390\/pharmaceutics12050459<\/a><\/div><\/div>
Potential implications of COVID-19 in non-alcoholic fatty liver disease.<\/div>
Prins GH, Olinga P<\/span> \u2014 DOI: 10.1111\/liv.14484<\/a><\/div><\/div>
Effect of Roux-en-Y gastric bypass on the bioavailability of metoprolol from immediate and controlled release tablets: a single oral dose study before and after surgery.<\/div>
Yska JP, Wanders JTM, Odigie B, Apers JA, Emous M, Tott\u00e9 ERE, Boerma EC, Ubels FL, Woerdenbag HJ, Frijlink HW, Wilffert B, van Roon EN<\/span> \u2014 DOI: 10.1136\/ejhpharm-2018-001804<\/a><\/div><\/div>
Design of a Gene Panel to Expose the Versatile Role of Hepatic Stellate Cells in Human Liver Fibrosis.<\/div>
van Dijk F, Hazelhoff CM, Post E, Prins GGH, Rombouts K, Poelstra K, Olinga P, Beljaars L<\/span> \u2014 DOI: 10.3390\/pharmaceutics12030278<\/a><\/div><\/div>
Development of an Orodispersible Film Containing Stabilized Influenza Vaccine.<\/div>
Tian Y, Bhide YC, Woerdenbag HJ, Huckriede ALW, Frijlink HW, Hinrichs WLJ, Visser JC<\/span> \u2014 DOI: 10.3390\/pharmaceutics12030245<\/a><\/div><\/div>
Reply.<\/div>
Hagedoorn P, Bawary W, Frijlink HW, Grasmeijer F<\/span> \u2014 DOI: 10.1016\/j.jaip.2019.11.023<\/a><\/div><\/div>
The Effect of Food on the Pharmacokinetics of Buspirone After Single Administration of a Sublingual Testosterone and Oral Buspirone Combination Tablet in Healthy Female Subjects.<\/div>
Gerritsen J, Bloemers J, van Rooij K, de Leede L, van der Geest R, Frijlink HW, Koppeschaar HPF, Olivier B, Tuiten A<\/span> \u2014 DOI: 10.1016\/j.esxm.2020.01.005<\/a><\/div><\/div>
A Pediatrics Utilization Study in The Netherlands to Identify Active Pharmaceutical Ingredients Suitable for Inkjet Printing on Orodispersible Films.<\/div>
Visser JC, Wibier L, Kiefer O, Orlu M, Breitkreutz J, Woerdenbag HJ, Taxis K<\/span> \u2014 DOI: 10.3390\/pharmaceutics12020164<\/a><\/div><\/div>
Time-Resolved Quantification of Nanoparticle Uptake, Distribution, and Impact in Precision-Cut Liver Slices.<\/div>
Bartucci R, \u00c5berg C, Melgert BN, Boersma YL, Olinga P, Salvati A<\/span> \u2014 DOI: 10.1002\/smll.201906523<\/a><\/div><\/div>
Orodispersible films as a personalized dosage form for nursing home residents, an exploratory study.<\/div>
Visser JC, Wibier L, Mekhaeil M, Woerdenbag HJ, Taxis K<\/span> \u2014 DOI: 10.1007\/s11096-020-00990-w<\/a><\/div><\/div>
Eradication of in cystic fibrosis patients with inhalation of dry powder tobramycin.<\/div>
Akkerman-Nijland AM, Yousofi M, Rottier BL, Van der Vaart H, Burgerhof JGM, Frijlink HW, Touw DJ, Koppelman GH, Akkerman OW<\/span> \u2014 DOI: 10.1177\/1753466620905279<\/a><\/div><\/div>
Murine Precision-cut Intestinal Slices as a Potential Screening Tool for Antifibrotic Drugs.<\/div>
Iswandana R, Pham BT, Suriguga S, Luangmonkong T, van Wijk LA, Jansen YJM, Oosterhuis D, Mutsaers HAM, Olinga P<\/span> \u2014 DOI: 10.1093\/ibd\/izz329<\/a><\/div><\/div>
Interview-based cross-sectional needs assessment to advance the implementation of an effective antibiotic stewardship program in Indonesian hospitals.<\/div>
Herawati F, Ananta SC, Parwitha IAA, Ressandy SS, Rahmatin NL, Rachmadini NA, Tangalobo VA, Setiasih , Yulia R, Hak E, Woerdenbag HJ, Avanti C<\/span> \u2014 DOI: 10.1016\/j.hpopen.2019.100002<\/a><\/div><\/div>
Investigating fibrosis and inflammation in an ex vivo NASH murine model.<\/div>
Gore E, Bigaeva E, Oldenburger A, Jansen YJM, Schuppan D, Boersema M, Rippmann JF, Broermann A, Olinga P<\/span> \u2014 DOI: 10.1152\/ajpgi.00209.2019<\/a><\/div><\/div>
Accepting higher morbidity in exchange for sacrificing fewer animals in studies developing novel infection-control strategies.<\/div>
Busscher HJ, Woudstra W, van Kooten TG, Jutte P, Shi L, Liu J, Hinrichs WLJ, Frijlink HW, Shi R, Liu J, Parvizi J, Kates S, Rotello VM, Schaer TP, Williams D, Grainger DW, van der Mei HC<\/span> \u2014 DOI: 10.1016\/j.biomaterials.2019.119737<\/a><\/div><\/div>
Inhibition of tyrosine kinase receptor signaling attenuates fibrogenesis in an ex vivo model of human renal fibrosis.<\/div>
Bigaeva E, Stribos EGD, Mutsaers HAM, Piersma B, Leliveld AM, de Jong IJ, Bank RA, Seelen MA, van Goor H, Wollin L, Olinga P, Boersema M<\/span> \u2014 DOI: 10.1152\/ajprenal.00108.2019<\/a><\/div><\/div>
Exploring organ-specific features of fibrogenesis using murine precision-cut tissue slices.<\/div>
Bigaeva E, Gore E, Mutsaers HAM, Oosterhuis D, Kim YO, Schuppan D, Bank RA, Boersema M, Olinga P<\/span> \u2014 DOI: 10.1016\/j.bbadis.2019.165582<\/a><\/div><\/div>
Inhomogeneous Distribution of Components in Solid Protein Pharmaceuticals: Origins, Consequences, Analysis, and Resolutions.<\/div>
Nguyen KTT, Frijlink HW, Hinrichs WLJ<\/span> \u2014 DOI: 10.1016\/j.xphs.2019.10.010<\/a><\/div><\/div>
A comparative analysis of changes in pMDI drug dose delivery before and after detergent coating using five antistatic valved holding chambers.<\/div>
Hagedoorn P, Bawary W, Frijlink HW, Grasmeijer F<\/span> \u2014 DOI: 10.1016\/j.jaip.2019.09.021<\/a><\/div><\/div>
Antifungal and biofilm inhibitory effect of Cymbopogon citratus (lemongrass) essential oil on biofilm forming by Candida tropicalis isolates; an in vitro study.<\/div>
Sahal G, Woerdenbag HJ, Hinrichs WLJ, Visser A, Tepper PG, Quax WJ, van der Mei HC, Bilkay IS<\/span> \u2014 DOI: 10.1016\/j.jep.2019.112188<\/a><\/div><\/div>
Efficacy and Safety of Peppermint Oil in a Randomized, Double-Blind Trial of Patients With Irritable Bowel Syndrome.<\/div>
Weerts ZZRM, Masclee AAM, Witteman BJM, Clemens CHM, Winkens B, Brouwers JRBJ, Frijlink HW, Muris JWM, De Wit NJ, Essers BAB, Tack J, Snijkers JTW, Bours AMH, de Ruiter-van der Ploeg AS, Jonkers DMAE, Keszthelyi D<\/span> \u2014 DOI: 10.1053\/j.gastro.2019.08.026<\/a><\/div><\/div>
Nasal gene expression changes with inhaled corticosteroid treatment in asthma.<\/div>
Boudewijn IM, Lan A, Faiz A, Cox CA, Brouwer S, Schokker S, Vroegop SJ, Nawijn MC, Woodruff PG, Christenson SA, Hagedoorn P, Frijlink HW, Choy DF, Brouwer U, Wisman M, Postma DS, Fingleton J, Beasley R, van den Berge M, Guryev V<\/span> \u2014 DOI: 10.1111\/all.13952<\/a><\/div><\/div><\/div><\/div>\n\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/details>\n\t\t\t\t\t<\/div>\n\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t","protected":false},"excerpt":{"rendered":"

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