{"id":2802,"date":"2026-02-20T11:59:49","date_gmt":"2026-02-20T10:59:49","guid":{"rendered":"https:\/\/ptb-rug.com\/?p=2802"},"modified":"2026-02-20T12:06:27","modified_gmt":"2026-02-20T11:06:27","slug":"prof-dr-peter-olinga","status":"publish","type":"post","link":"https:\/\/ptb-rug.com\/?p=2802","title":{"rendered":"Prof. dr. Peter Olinga"},"content":{"rendered":"
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Ex vivo model<\/strong>
\nThe Organ Slice Lab is led by Prof. dr. Peter Olinga and explores precision-cut tissue slices (PCTS) as a highly relevant and translational model to elucidate the pathogenesis, treatment, and biomarker research of organ fibrosis.<\/p>\n

We work from the postulate that current therapeutic gaps in fibrosis\u2014the excessive production of extracellular matrix\u2014stem from a failure to account for the complex\u00a0in vivo<\/i>\u00a0architecture and cellular composition of human organs. To address this, we utilize viable tissue explants derived from healthy and diseased human liver, kidney, and intestine to investigate disease pathogenesis, evaluate potential treatments, and conduct biomarker research. This methodology enables precise reconstruction of disease mechanisms while contributing to the reduction of laboratory animal use in pharmaceutical research.<\/p>\n<\/div>\n<\/div>\n<\/div>\n

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Core pillars:<\/b><\/b><\/p>\n